Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Human chromosome Y and SRY

V C Shah1, V Smart

  • 1Zoology Department, Gujarat University, Ahmedabad, India.

Cell Biology International
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

The SRY gene

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

G(2) chromosomal radiosensitivity in Danish survivors of childhood and adolescent cancer and their offspring.

British journal of cancer·2005
Same author

Chromosomal radiosensitivity: a study of the chromosomal G(2) assay in human blood lymphocytes indicating significant inter-individual variability.

Mutation research·2003
Same author

The G2 chromosomal radiosensitivity assay.

International journal of radiation biology·2002
Same author

Three siblings with Harlequin Ichthyosis in an Indian family.

Early human development·1996
Same author

Cost-effectiveness of magnetic resonance imaging in specific situations in India.

Academic radiology·1996
Same author

Incomplete gonadal dysgenesis.

Urologia internationalis·1996

Area of Science:

  • Genetics and Molecular Biology
  • Developmental Biology

Background:

  • The SRY gene is crucial for male sex determination in humans.
  • Understanding SRY's precise location and function is key to studying sex development.

Purpose of the Study:

  • To pinpoint the SRY gene's location on the human Y chromosome.
  • To elucidate the SRY gene's DNA sequence and mechanism of action.
  • To explore SRY's evolutionary conservation and interactions in male sex determination.

Main Methods:

  • Analysis of sex reversal cases with SRY gene deletions.
  • Investigation of SRY gene cross-linking and mutation studies.
  • Comparative genomics to assess SRY similarity with mouse Sry.

Main Results:

Related Experiment Videos

  • The precise location of the SRY gene on the human Y chromosome has been identified.
  • Insights into the DNA sequence and functional mechanism of SRY have been gained.
  • Homology between human SRY and mouse Sry suggests conserved function in mammalian sex determination.

Conclusions:

  • SRY gene's location and function are critical for male sex determination.
  • Comparative studies highlight conserved roles of SRY in mammalian development.
  • Further research into SRY interactions can illuminate sex development pathways.