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Published on: July 25, 2011
Langerhans' cell histiocytosis: report of three cases with unusual oral soft tissue involvement
D B Cleveland1, K M Goldberg, J S Greenspan
1Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA.
Abstract:
Three cases of Langerhans' cell histiocytosis (histiocytosis X) are reported in which the clinical presentations were (1) soft-tissue enlargements, (2) oral ulcerations, and (3) leukoplakia. Each case was without bone involvement at the time of diagnosis, and two patients were older than 60 years of age. Definitive diagnoses were aided with the use of immunohistochemistry.

