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Neonatal meningitis in northern Jordan
A S Daoud1, M al-Sheyyab, F Abu-Ekteish
1Department of Paediatrics, Jordan University of Science and Technology, Irbid, Jordan.
Journal of Tropical Pediatrics
|October 1, 1996
Summary
Neonatal meningitis in Jordan shows Klebsiella as a key pathogen. Early recognition of bulging fontanelles and altered sensorium is crucial for better outcomes in newborns.
Area of Science:
- Pediatrics
- Infectious Diseases
- Neonatology
Background:
- Neonatal meningitis poses a significant threat to infant health.
- Understanding regional variations in pathogens and outcomes is essential for effective treatment.
Purpose of the Study:
- To investigate the clinical spectrum and characteristics of neonatal meningitis in Northern Jordan.
- To identify key risk factors and predictors of mortality and neurological sequelae.
Main Methods:
- Prospective study over 2.5 years in two referral hospitals.
- Analysis of 53 cases of neonatal meningitis.
- Identification of bacterial pathogens and assessment of clinical features and outcomes.
Main Results:
- Incidence of 1.1 per 1000 live births.
- Klebsiella species (40%) and Enterobacter (19%) were the most common pathogens.
- Mortality rate was 32%, with 39% neurological sequelae.
- Bulging anterior fontanelle predicted mortality; altered sensorium predicted sequelae.
Conclusions:
- Klebsiella is an important neonatal meningitis pathogen in this region.
- Cefotaxime or ceftazidime plus ampicillin are recommended initial antibiotics.
- Continuous surveillance and prompt recognition of clinical signs are vital.