Related Experiment Videos
[Fisher's syndrome with profound hypotension]
Rinsho Shinkeigaku = Clinical Neurology
|June 1, 1996
Summary
Fisher's syndrome can cause severe hypotension, a rare complication. Cardiovascular monitoring is crucial for patients with Fisher's syndrome due to potential dysautonomia.
Area of Science:
- Neurology
- Immunology
Background:
- Fisher's syndrome is a rare neurological disorder characterized by ophthalmoplegia, ataxia, and areflexia.
- Cardiovascular dysautonomia is a known complication of Guillain-Barré syndrome but is rarely reported in Fisher's syndrome.
Observation:
- A 70-year-old female with Fisher's syndrome developed profound hypotension during plasmapheresis.
- The patient required intensive vasopressor support to maintain blood pressure, indicating significant cardiovascular dysautonomia.
- Echocardiography revealed normal cardiac output, suggesting reduced vascular resistance as the cause of hypotension.
Findings:
- This case highlights the potential for severe cardiovascular dysautonomia in Fisher's syndrome.
- Hypotension in this patient was attributed to decreased vascular resistance, not impaired cardiac function.
- The patient's condition necessitated prolonged vasopressor and fluid management.
Implications:
- Cardiovascular function must be closely monitored in all patients diagnosed with Fisher's syndrome.
- Early recognition and management of cardiovascular dysautonomia are essential to prevent adverse outcomes.
- This case expands the understanding of potential autonomic nervous system involvement in Fisher's syndrome.