Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chemoreception: tasting the sweet and the bitter

B Lindemann1

  • 1Department of Physiology, Saarland University, Homburg, Germany.

Current Biology : CB
|October 1, 1996
PubMed
Summary

A newly identified signaling protein, gustducin, is crucial for detecting bitter and sweet tastes. This taste-tissue specific protein advances our understanding of taste molecular mechanisms.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

["With all suitable means". Off-label-use and public statutory employers' liability insurance].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2013
Same author

A follow-up study on fall and fracture incidence in long-term care including the role of formal caregiver time on fall incidence rates.

Zeitschrift fur Gerontologie und Geriatrie·2006
Same author

[Medical care in the nursing home].

Zeitschrift fur Gerontologie und Geriatrie·2005
Same author

[Minimal Change Glomerulonephritis].

Der Internist·2003
Same author

[Abilities and restrictions of nursing home residents. Evaluation with the Minimum Data Set of the Resident Assessment Instrument].

Zeitschrift fur Gerontologie und Geriatrie·2003
Same author

Hans Ussing, experiments and models.

The Journal of membrane biology·2002

Area of Science:

  • Molecular biology
  • Sensory neuroscience
  • Biochemistry

Background:

  • Understanding taste transduction at the molecular level has been limited compared to other sensory systems.
  • Key signaling pathways involved in taste perception remain largely uncharacterized.

Purpose of the Study:

  • To identify and characterize novel proteins involved in taste transduction.
  • To elucidate the molecular basis of bitter and sweet taste perception.

Main Methods:

  • Investigated the tissue specificity of the G protein alpha subunit gustducin.
  • Assessed the role of gustducin in bitter and sweet taste responses.

Main Results:

  • Gustducin was found to be specifically expressed in taste tissues.
  • Gustducin was demonstrated to be essential for mediating both bitter and sweet taste signals.

Conclusions:

  • Gustducin is a critical taste-tissue specific signaling protein.
  • The discovery of gustducin's role significantly advances the understanding of molecular mechanisms underlying taste transduction.

Related Experiment Videos