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Steroid-responsive Rosai-Dorfman disease
J I Antonius1, S M Farid, A Baez-Giangreco
1Department of Pathology, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
Pediatric Hematology and Oncology
|November 1, 1996
Summary
Rosai-Dorfman disease (RDD) in a child presented with skin lesions and lymphadenopathy. Oral prednisolone led to rapid symptom resolution, indicating steroid dependence for this rare condition.
Area of Science:
- Pediatric Pathology
- Dermatology
- Immunology
Background:
- Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy (SHML), is a rare benign proliferative disorder of histiocytes.
- Clinical presentation typically involves painless lymphadenopathy, fever, and extranodal involvement.