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Related Experiment Videos

Steroid-responsive Rosai-Dorfman disease

J I Antonius1, S M Farid, A Baez-Giangreco

  • 1Department of Pathology, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.

Pediatric Hematology and Oncology
|November 1, 1996
PubMed
Summary

Rosai-Dorfman disease (RDD) in a child presented with skin lesions and lymphadenopathy. Oral prednisolone led to rapid symptom resolution, indicating steroid dependence for this rare condition.

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Area of Science:

  • Pediatric Pathology
  • Dermatology
  • Immunology

Background:

  • Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy (SHML), is a rare benign proliferative disorder of histiocytes.
  • Clinical presentation typically involves painless lymphadenopathy, fever, and extranodal involvement.