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Clinical application of nonselective assisted hatching of human embryos
Y Hu1, D I Hoffman, W S Maxson
1Northwest Center for Infertility and Reproductive Endocrinology, Margate, Florida 33063, USA.
Objective:
To evaluate the effect of nonselective assisted hatching on pregnancy rate (PR) and to provide an alternative and simplified method for clinical application of assisted hatching.
Design:
Retrospective analysis of clinical data.
Setting:
Private infertility practice.
Patient(S):
Women from 258 consecutive stimulated IVF cycles.
Intervention(S):
Assisted hatching was performed on each transferred embryo regardless of patient history, embryo morphology, or other selection criteria routinely applied to many IVF programs.
Main Outcome Measure(S):
Pregnancy, live birth, and implantation rates.
Result(S):
Of 258 consecutive patients who had nonselective assisted hatching, 109 (42%) had clinical pregnancies, with 93 (36%) live births and 178 (20%) embryos implanted.
Conclusion(S):
Nonselective assisted hatching resulted in an acceptable PR and provided an alternative and simplified method for clinical application of assisted hatching.