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Phase II study of 5-fluorouracil and leucovorin in recurrent primary brain tumor
T L Cascino1, M H Veeder, J C Buckner
1Mayo Clinic, Rochester, MN 55905, USA.
Journal of Neuro-Oncology
|December 1, 1996
Abstract:
Thirty patients with recurrent primary brain tumors were treated with a combination of 5-fluorouracil and leucovorin. There were three responses seen. Toxicity consisted of stomatitis, diarrhea, and hematological suppression. 5-fluorouracil and leucovorin would appear to be minimally effective in recurrent brain tumors.