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Related Experiment Videos

Single lead VDD pacing: multicenter study

I E Ovsyscher1, A Katz, S Rosenheck

  • 1Arrhythmia Service, Soroka Medical Center, Beer-Sheva, Israel.

Pacing and Clinical Electrophysiology : PACE
|November 1, 1996
PubMed
Summary
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The Thera VDD pacing system offers reliable atrial sensing and ventricular pacing for AV block patients. This single-lead system demonstrates a 96% survival rate at two years, simplifying implantation and preserving AV synchrony.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Devices

Background:

  • Atrioventricular (AV) block with normal sinoatrial (SA) node function necessitates pacing strategies that maintain AV synchrony.
  • Single-lead VDD pacing offers advantages over dual-lead systems, including simplified implantation and preservation of AV synchrony.

Purpose of the Study:

  • To evaluate the performance of the Medtronic Thera VDD pacing system.
  • To assess the effectiveness of atrial sensing and ventricular pacing capabilities of the Thera VDD system.

Main Methods:

  • Implantation of Thera VDD systems (Models 8948 or 8968) in 165 patients (150 adults, 15 children) with AV block and normal SA node function.
  • Intraoperative electrical measurements and assessment of atrial signal amplitudes.
  • Follow-up evaluation of system performance, lead stability, and reprogramming events over 24 months.

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Main Results:

  • Intraoperative ventricular electrical measurements were comparable to VVI pacemakers.
  • Mean atrial signal amplitude at implantation was 4.1 ± 1.9 mV, with stable measurements over 24 months.
  • Lead repositioning occurred in 1.4% of patients; reprogramming to VVI was needed in 4.2% due to atrial fibrillation or undersensing.

Conclusions:

  • The Thera VDD pacing system is a reliable and manageable option for patients with AV block and normal SA node function.
  • The system demonstrates dependable atrial sensing and ventricular pacing, with a high 2-year survival rate of 96%.