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Evolution of atrial signals from a single lead VDD pacemaker. AddVent European Multicentre Study Group
1Bristol Heart Institute, United Kingdom.
Pacing and Clinical Electrophysiology : PACE
|November 1, 1996
Summary
This study found that the Pacesetter AddVent VDD pacing system provides reliable atrial sensing. Atrial signal amplitudes, though initially variable, stabilize and ensure effective AV synchronous pacing over time.
Area of Science:
- Cardiology
- Biomedical Engineering
- Medical Devices
Background:
- Assessing atrial sensing in VDD pacing systems is crucial for effective AV synchrony.
- The Pacesetter AddVent system utilizes a novel quadripolar lead for atrial sensing.
Purpose of the Study:
- To evaluate the atrial sensing performance of the Pacesetter AddVent single pass VDD pacing system.
- To determine the reliability of atrial sensing for AV synchronous pacing.
Main Methods:
- Prospective multicenter study involving 101 implants of the Pacesetter AddVent system.
- Analysis of P wave amplitude and Holter monitoring for AV synchrony over time.
- Evaluation of lead electrode configuration and interelectrode spacing for atrial sensing.
Main Results:
- Mean P wave amplitude showed initial variability but stabilized over the first year.
- High mean AV synchrony (98.2%) was achieved, with 83% of patients exceeding 99%.
- Low incidence of atrial fibrillation (2%) and no sinus bradycardia or oversensing were reported.
Conclusions:
- The Pacesetter AddVent pacing system demonstrates adequate and reliable atrial sensing capabilities.
- The system ensures effective AV synchronous pacing, even with initial variations in atrial signal amplitude.
- The quadripolar lead design supports consistent performance in patients with heart block.