Mannitol injections: with or without filter needles? A cost-effectiveness analysis

A clinical economic evaluation was conducted to assess the cost-effectiveness of filtration of i.v. mannitol injections. Clinical decision analysis was used to model the costs and benefits of using filter needles for undiluted, i.v. push injections of mannitol 25%. Sensitivity analysis conducted by varying all uncertain variables to test best and worst case scenarios revealed that the use of filter needles is a cost-effective measure in all relevant scenarios.