Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior

¹Department of Pharmacognosy, School of Pharmacy, Shanghai Medical University, People's Republic of China.

|November 1, 1996

Abstract:

Two new lignans, interiotherins A (1) and B (2), along with two known lignans, angeloylgomisin R (3) and schisantherin D (4), were isolated from Kadsura interior. Their structures and stereochemistries were determined from spectral data. Compounds 1 and 4 inhibit HIV replication with EC50 values of 3.1 and 0.5 micrograms/mL, respectively.

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Abstract:

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