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[Treatment with hydroxyurea of polycythemia vera in a 11 year-old child]
1Service de pédiatrie, gastroentérologie et génétique médicale, CHRU de Lille, France.
Abstract
Background:
Polycythemia vera is a very rare disease in childhood; its treatment for this reason is not well established.
Case Report:
An 11-year-old boy was admitted for polycythemia vera. The three classical major criteria for this condition were present and no cause for secondary polyglobulia could be recognized. The patient was given hydroxyurea. Three years later, he is well with hematocrit below 50%.
Conclusions:
Oral continuous myelosuppressive therapy with hydroxyurea may be proposed in children if there is no HLA-matched family member. Long-term follow-up is nevertheless necessary in order to detect relapse or side-effects of the treatment.