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Related Experiment Videos

[Body weight changes under psychotropic treatment]

D Bernard1, C Lançon, T Bougerol

  • 1Service hospitalo-universitaire du Pr Scotto, Hôpital Sainte-Marguerite, Marseille.

Presse Medicale (Paris, France : 1983)
|September 28, 1996
PubMed
Summary
This summary is machine-generated.

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Psychotropic medications, including neuroleptics and lithium, can cause weight gain, which varies by drug and patient history. Understanding these complex mechanisms is crucial for managing this common side effect.

Area of Science:

  • Pharmacology
  • Clinical Psychology

Context:

  • Weight gain is a frequent adverse effect associated with various psychotropic medications.
  • The extent of weight gain is influenced by drug type, dosage, and treatment duration.
  • Patient history and individual factors play a role in the gradual onset of this side effect.

Purpose:

  • To review the common side effect of weight gain associated with psychotropic drug use.
  • To explore the varying impact of different drug classes (neuroleptics, antidepressants, lithium, benzodiazepines) on body weight.
  • To discuss the known and hypothesized etiopathogenic mechanisms behind drug-induced weight gain.

Summary:

  • Neuroleptics (specifically phenothiazines and benzamides) and lithium are strongly linked to significant weight gain.
  • The direct impact of antidepressants on weight remains debated, and data on benzodiazepines is limited.

Related Experiment Videos

  • Weight gain is not an inevitable outcome and results from complex, multifactorial influences, including biochemical, pharmacological, psychological, and environmental factors.

    • Impact:

    • Highlights the need for further research into the mechanisms of psychotropic-induced weight gain.
    • Informs clinical practice regarding the potential for weight gain with specific medications.
    • Emphasizes that weight gain is a complex phenomenon requiring personalized management strategies.