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Complexity, communication between cells, and identifying the functional components of living systems: some
1Department of Physiology, Medical College of Virginia Commonwealth University, Richmond 23298-0551, USA. Mikulecky@gems.vcu.edu
Acta Biotheoretica
|November 1, 1996
Summary
This review explores Robert Rosen's rigorous definition of complexity, offering a new framework for understanding living systems beyond the Newtonian Paradigm. It highlights how our perception of complexity is shaped by scientific history and knowledge.
Area of Science:
- Theoretical biology
- Philosophy of science
- Systems theory
Background:
- The concept of complexity in theoretical biology is ill-defined and lacks a universal meaning.
- Existing notions of complexity are often subjective and influenced by historical scientific paradigms.
- The reductionist/mechanistic Newtonian Paradigm has historically dominated scientific epistemology.
Purpose of the Study:
- To review the development of the concept of complexity in theoretical biology.
- To examine Robert Rosen's rigorous definition of complexity as a criterion for studying living systems.
- To explore the relationship between complexity, scientific epistemology, and the definition of life.
Main Methods:
- Analysis of Robert Rosen's definition of complexity and the 'modelling relation'.
- Historical review of scientific epistemology and its influence on the perception of complexity.
- Examination of concepts like chaotic dynamics and the second law of thermodynamics in relation to complexity.
- Exploration of causal relations in complex systems.
Main Results:
- Rosen's definition provides a precise and rigorous categorization of systems, particularly living ones.
- The perception of complexity is largely a product of historical scientific processes and a reaction to reductionism.
- Popular concepts like 'edge of chaos' lack rigor when examined through Rosen's framework.
- A clear distinction in causal relations differentiates complex from simple systems, offering insight into life.
Conclusions:
- Rosen's definition of complexity offers a valuable new approach to studying living systems.
- Understanding complexity requires acknowledging the subjective nature of scientific practice and historical context.
- This rigorous view of complexity moves beyond popular, less defined notions and provides a foundation for defining life.
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