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Neuromuscular blockade in the management of cerebral palsy
L A Koman1, J F Mooney, B P Smith
1Department of Orthopaedic Surgery, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27157-1070, USA.
Journal of Child Neurology
|November 1, 1996
Abstract:
Neuromuscular blocking agents-45% alcohol, 4% to 6% aqueous phenol, local anesthetics, and botulinum A toxin-have been used for many years in the evaluation and management of spasticity and movement disorders in children with cerebral palsy. Recent reports suggest that longer-acting neuromuscular blocking agents may impact positively on the natural history of dynamic deformity and improve health-related quality of life. This review includes the mechanism of action, techniques, indications, complications, and clinical outcomes associated with these agents.