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Updated: Aug 27, 2026

Detection and Genogrouping of Noroviruses from Children's Stools By Taqman One-step RT-PCR
15:16

Detection and Genogrouping of Noroviruses from Children's Stools By Taqman One-step RT-PCR

Published on: July 22, 2012

[Nosocomial rotavirus infections in children]

J Táborská1, P Pazdiora

  • 1Infekcní klinika, FN Plzen.

Casopis Lekaru Ceskych
|August 21, 1996
PubMed

Insights

Rotavirus gastroenteritis is a frequent cause of hospitalizations in young children. Nosocomial rotavirus infections prolong hospital stays but have a favorable prognosis and are not seasonal.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Gastroenterology

Context:

  • Rotaviruses are a leading cause of severe diarrheal diseases in children globally, accounting for a significant proportion of hospital admissions.
  • They are also a primary etiological agent of nosocomial (hospital-acquired) diarrheal infections.

Purpose:

  • To analyze the etiology of diarrhea in children under three years of age, with a specific focus on rotavirus as a cause of nosocomial infection.
  • To understand the incidence, clinical presentation, and outcomes of rotavirus-related nosocomial infections in hospitalized children.

Summary:

  • A study of 2002 children under three found rotavirus in 25.4% of diarrheal cases. Nosocomial rotavirus infection occurred in 4.0% of diarrheal patients, typically between days 4-6 of hospitalization.
  • While rotavirus infections show seasonal peaks, nosocomial cases did not follow this pattern. Clinical presentation, often with isoosmolal dehydration, was similar to community-acquired cases.
  • Elevated aminotransferases were observed in most patients. Symptomatic treatment was effective, and the prognosis was favorable, though nosocomial infections extended hospitalization by an average of five days.

Impact:

  • Nosocomial rotavirus gastroenteritis presents a significant challenge in pediatric hospital settings, particularly affecting young children.
  • Current understanding does not provide means to prevent these infections, which lack seasonal patterns and distinct clinical features.
  • Despite a favorable prognosis, nosocomial rotavirus infections contribute to prolonged hospital stays, highlighting the need for effective control strategies.
Abstract

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