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Ventricular volume elasticity: a component of cardiovascular control?
T Encke1, B Flemming, D Roloff
1Universitätsklinikum Charité, Medizinische Fakultät, Humboldt-Universität zu Berlin, Germany.
Journal of the Autonomic Nervous System
|March 7, 1996
Summary
Cardiac volume elasticity is an independent factor in cardiovascular control. This study measured its dynamic changes and found it interacts with other key cardiovascular parameters.
Area of Science:
- Cardiovascular Physiology
- Biomedical Engineering
Background:
- Complex physiological networks involve receptor stimulation leading to effector responses.
- The role of cardiac chamber's dynamic volume elasticity in cardiovascular regulation requires further elucidation.
Purpose of the Study:
- To determine if the heart chamber's dynamical volume elasticity is an independent component of cardiovascular control.
- To investigate the influence of baro- and chemoreflexes on cardiac elasticity.
Main Methods:
- Dynamical volume elasticity was calculated using changes in eigenfrequency from a modified catheter transducer system.
- Carotid baro- and chemoreflexes were stimulated to observe their effects.
Main Results:
- Carotid baro- and chemoreflexes differentially affected end-diastolic pressure, contractility, and calculated diastolic and systolic elasticity.
- The study successfully measured the dynamical volume elasticity of the heart chamber.
Conclusions:
- Cardiac volume elasticity is an independent element within the cardiovascular control system.
- It interacts with other physiological parameters to maintain cardiovascular homeostasis.