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Does corticosteroid metabolism in target organs affect the cardiovascular system?

K Hierholzer1, I Lichtenstein, H Siebe

  • 1Department of Clinical Physiology, University Clinic Benjamin Franklin, Free University of Berlin, Germany.

Journal of the Autonomic Nervous System
|March 7, 1996
PubMed
Summary

The enzyme 11 beta-hydroxysteroid oxidoreductase (11 beta-HSOR) is crucial for corticosteroid metabolism in various rat organs. Its inhibition can cause aldosterone-like effects by altering glucocorticoid receptor binding.

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