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Related Experiment Videos

Tuberculosis outbreak in a Texas prison, 1994

D Bergmire-Sweat1, B J Barnett, S L Harris

  • 1Infectious Disease Epidemiology and Surveillance Division, Texas Department of Health, Austin 78756, USA.

Epidemiology and Infection
|December 1, 1996
PubMed
Summary
This summary is machine-generated.

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A 1994 Texas prison tuberculosis outbreak infected over 100 inmates. Standard infection control failed, highlighting the need for enhanced strategies in special populations like mentally retarded inmates.

Area of Science:

  • Infectious Diseases
  • Public Health
  • Epidemiology

Background:

  • A significant tuberculosis outbreak occurred in a Texas prison in 1994.
  • The affected population included mentally retarded inmates, a vulnerable group.
  • Standard infection control measures proved insufficient to contain the outbreak.

Purpose of the Study:

  • To investigate the transmission dynamics of tuberculosis within a correctional facility.
  • To identify risk factors associated with tuberculosis infection in this inmate population.
  • To evaluate the effectiveness of existing infection control policies.

Main Methods:

  • Conducted a case-control study involving 230 inmates (119 infected/diseased, 111 controls).
  • Utilized polymerase chain reaction (PCR) based DNA fingerprinting to confirm identical Mycobacterium tuberculosis strains.

Related Experiment Videos

  • Analyzed inmate cell assignments, job duties, educational classes, and reviewed medical charts.

    • Main Results:

    • Identified 15 cases of tuberculosis, with 8 confirmed by positive cultures.
    • Tuberculosis transmission was significantly associated with residing in D Wing (OR=25.84), attending Classroom A (OR=8.34), and working on the utility crew (OR=2.52).
    • The index case had a history of isoniazid (INH) chemoprophylaxis.

    Conclusions:

    • Standard tuberculosis infection control policies were inadequate for this high-risk prison population.
    • Specific locations and activities within the prison facilitated tuberculosis transmission.
    • Enhanced and tailored infection control strategies are crucial for correctional facilities.