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Related Experiment Videos

Apheresis. New opportunities

N Bandarenko1, H G Owen, D C Mair

  • 1Department of Pathology and Laboratory Medicine, University of North Carolina Hospital, Chapel Hill, USA.

Clinics in Laboratory Medicine
|December 1, 1996
PubMed
Summary
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Recent apheresis techniques improve stem cell collection and treatment for various diseases. Advances in apheresis, including photopheresis, offer new therapeutic possibilities and highlight future directions.

Area of Science:

  • Medical Technology
  • Hematology
  • Immunology

Background:

  • Apheresis technology has seen significant advancements impacting diverse clinical applications.
  • Key areas include improvements in cell collection, evolving therapeutic roles, and patient management strategies.

Purpose of the Study:

  • To review recent progress in apheresis technology and its clinical implications.
  • To highlight advancements in granulocyte and stem cell collection, intravenous gamma globulin use, and apheresis modalities like photopheresis.

Main Methods:

  • Review of current literature and clinical practices in apheresis.
  • Discussion of improvements in apheresis equipment and protocols.
  • Analysis of patient selection and fluid replacement in apheresis procedures.

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Main Results:

  • Enhanced efficiency in granulocyte and peripheral blood stem cell collection and mobilization.
  • Clarified role of intravenous gamma globulin and importance of patient assessment.
  • Progress in affinity apheresis and photopheresis techniques demonstrated.

Conclusions:

  • Current apheresis trends show limitations but significant promise for treating various diseases.
  • Future directions in apheresis technology are inspired by these ongoing developments and their therapeutic potential.