[Characterization of pancreatic casein plasteins]
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Updated: Nov 3, 2026

A System for ex vivo Culturing of Embryonic Pancreas
Published on: August 27, 2012
P Chr Lorenzen1, A Schieber, H Brückner
1Institut für Chemie und Physik der Bundesanstalt für Milchforschung, Kiel, Deutschland.
Abstract:
Characterization of pancreatic casein plasteins. In the course of the plastein reaction hydrophobic peptides concentrate mainly in the aggregates (plasteins), whilst hydrophilic peptides remain in solution (supernatant). Liquid chromatographic and sequence analytical studies of pancreatic casein plasteins have shown that the aggregates consist mainly of the free amino acids tyrosine, phenylalanine and tryptophan. Plasteins contain, in addition, short-chain peptides, particularly from the C-terminal of beta-casein. Characterization of the functional properties of the plasteins has shown clearly that aggregation of the short-chain peptides and free amino acids is brought by non-covalent, hydrophobic and ionogenic interactions. In the supernatants resulting from the plastein reaction caseinophosphopeptide sequences, in particular from alpha s-casein, were determined.
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