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Coenzyme-B12 therapy in acute viral hepatitis
Scandinavian Journal of Infectious Diseases
|January 1, 1977
Summary
Coenzyme-B12 supplementation may improve liver health in patients with viral hepatitis. This vitamin form showed faster recovery of serum aminotransferase levels compared to cyanocobalamin in a hepatitis A study.
Area of Science:
- Hepatology
- Nutritional Biochemistry
- Virology
Background:
- Viral hepatitis causes liver damage and reduced vitamin storage.
- Vitamin B12 is essential for tissue repair and liver function.
- Coenzyme-B12 is a newly synthesized form of vitamin B12.
Purpose of the Study:
- To evaluate the efficacy of coenzyme-B12 in treating viral hepatitis.
- To compare the effects of coenzyme-B12 and cyanocobalamin on liver recovery.
Main Methods:
- Two groups of hepatitis A patients were treated.
- One group received coenzyme-B12, the other received cyanocobalamin.
- Serum aminotransferase (S-ALAT) levels were monitored.
Main Results:
- The coenzyme-B12 group exhibited a faster normalization of S-ALAT levels.
- Coenzyme-B12 demonstrated a favorable effect on damaged liver cells.
- Improved absorption and hepatic accumulation of coenzyme-B12 were suggested.
Conclusions:
- Coenzyme-B12 may be more effective than cyanocobalamin for liver recovery in viral hepatitis.
- Further research into coenzyme-B12 for liver conditions is warranted.
- Enhanced absorption and liver accumulation contribute to coenzyme-B12's efficacy.