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Updated: Aug 18, 2026

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
Published on: March 17, 2014
[Epidemiology of acute bronchopulmonary infections in children]
1Service de pneumologie, Hôpital Lenval, Nice.
Insights
Acute lower respiratory infections are a major cause of death in young children, particularly in developing nations. Factors like young age, indoor pollution, and malnutrition increase susceptibility to these common childhood infections.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Abstract:
In infants and young children acute lower respiratory infection is the most common cause of morbidity and death especially in developing countries. Factors that contribute to the increased susceptibility to respiratory pathogens include young age, season, sex, indoor pollution, large family size, malnutrition, low immunocompetence, socioeconomic disadvantage. The epidemiology of acute respiratory infections in childhood seems similar worldwide. In all countries, respiratory syncytial virus, parainfluenzae virus 1 and 3 influenzae A and B viruses and adenovirus are reported to be the main causes of acute respiratory infections. Six microorganisms are responsible of 90% of documented acute bacterial pulmonary infections, Streptococcus pneumoniae, Mycoplasma pneumoniae, Chlamydia pneumoniae, Chlamydia trachomatis, Haemophilus influenzae, Staphylococcus. Mixed viral and bacterial infections occur frequently (30%). The role of respiratory viruses in predisposing to colonization and invasion of bacterial organisms has often been suggested. In recent years acquired resistance against antibiotic for H. influenzae and S. pneumoniae has emerged.
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