Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nitric oxide in exhaled air

J O Lundberg1, E Weitzberg, J M Lundberg

  • 1Dept of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden.

The European Respiratory Journal
|December 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nitrate: "the source makes the poison".

Critical reviews in food science and nutrition·2024
Same author

Dietary nitrate attenuates high-fat diet-induced obesity via mechanisms involving higher adipocyte respiration and alterations in inflammatory status.

Redox biology·2019
Same author

Mechanisms underlying blood pressure reduction by dietary inorganic nitrate.

Acta physiologica (Oxford, England)·2018
Same author

Heparin-binding protein as a biomarker of post-injury sepsis in trauma patients.

Acta anaesthesiologica Scandinavica·2018
Same author

Effects of nitrate supplementation in trained and untrained muscle are modest with initial high plasma nitrite levels.

Scandinavian journal of medicine & science in sports·2017
Same author

Therapeutic effects of inorganic nitrate and nitrite in cardiovascular and metabolic diseases.

Journal of internal medicine·2015
Same journal

Beyond the 5th percentile: rethinking diagnostic thresholds in pulmonary function testing.

The European respiratory journal·2026
Same journal

A Transcriptomic Atlas of Chronic Lung Allograft Dysfunction.

The European respiratory journal·2026
Same journal

Risk of cancer and mortality in patients with interstitial lung diseases: Danish cohort study.

The European respiratory journal·2026
Same journal

Proposing a minimal important difference in NTproBNP in pulmonary arterial hypertension.

The European respiratory journal·2026
Same journal

Unlocking growth potential: Ivacaftor therapy and developmental gains in lung and height in a cohort study of children and young adults with cystic fibrosis.

The European respiratory journal·2026
Same journal

Decoding the Lymphangioleiomyomatosis (LAM) Niche Microenvironment <i>via</i> Integrative Analysis of Single Cell Multiomics and Spatial Transcriptomics.

The European respiratory journal·2026
See all related articles

Nitric oxide (NO) levels in exhaled air differ between healthy individuals and those with inflammatory airway diseases. Measuring exhaled NO shows potential for diagnosing and monitoring conditions like asthma and cystic fibrosis.

Area of Science:

  • Respiratory Medicine
  • Biomedical Engineering

Background:

  • Nitric oxide (NO) is increasingly measured in exhaled air.
  • In healthy individuals, exhaled NO primarily originates from nasal airways.
  • Inflammatory airway diseases alter NO excretion, changing exhaled NO levels.

Purpose of the Study:

  • To explore the regulation of airway nitric oxide production.
  • To identify factors influencing airway nitric oxide excretion.
  • To evaluate the clinical utility of exhaled NO measurements.

Main Methods:

  • Development of new techniques to measure NO release at different airway levels.
  • Comparison of exhaled NO levels in healthy subjects, asthmatics, cystic fibrosis patients, and Kartagener's syndrome patients.

Related Experiment Videos

Main Results:

  • Asthmatics exhibit increased orally-exhaled NO.
  • Cystic fibrosis and Kartagener's syndrome patients show reduced nasal NO release.
  • Exhaled NO levels vary significantly based on airway location and disease state.

Conclusions:

  • Exhaled NO measurements offer potential for noninvasive diagnosis and monitoring of inflammatory airway diseases.
  • Understanding NO production regulation is crucial for clinical application.
  • Further research is needed to fully evaluate the clinical usefulness of exhaled NO.