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[Neonatal convulsions in health care. I. Incidence, etiology and clinical aspects]

M C Carrascosa1, A Mariínez-Gutiérrez, I Onsurbe

  • 1Servicio de Neuropediatria, Hospital General de Albacete, España.

Revista De Neurologia
|October 1, 1996
PubMed

Insights

Neonatal convulsions occurred in 25 newborns, with higher incidence in preterm infants. Poor prognosis was linked to specific risk factors, unlike treatable metabolic causes.

Area of Science:

  • Neonatal neurology
  • Pediatric epidemiology
  • Clinical obstetrics

Context:

  • Neonatal convulsions represent a significant clinical challenge in pediatrics.
  • Understanding the incidence and etiology of these events is crucial for improving outcomes.
  • Previous studies have varied in their findings regarding causes and prognosis.

Purpose:

  • To determine the incidence, etiology, and course of neonatal convulsions in the Albacete Health District.
  • To analyze the outcomes and identify prognostic factors in affected newborns.

Summary:

  • A retrospective cohort study of 12,427 newborns identified 25 cases of neonatal convulsions.
  • The incidence varied significantly by gestational age, being highest in preterm and immature infants.
  • Leading etiologies included hypoxic-ischemic encephalopathy (32%), cerebral malformations (24%), and intracranial hemorrhage (16%).
  • Mortality was 40%, with 32% experiencing sequelae; only 28% had normal development.
  • Poor prognosis was associated with antepartum fetal distress, cerebral malformations, and metabolic encephalopathies, contrasting with better outcomes for treatable conditions like hypoglucemia.

Impact:

  • This study highlights a potentially increased incidence of neonatal convulsions with poorer prognostic indicators in the studied region.
  • Findings emphasize the importance of identifying high-risk pregnancies and newborns.
  • The data provides valuable epidemiological insights for neonatal care and resource allocation.
Abstract

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