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Related Experiment Videos

Auditory evoked potentials in postconcussive syndrome

M E Drake1, S J Weate, S A Newell

  • 1Department of Neurology, Ohio State University College of Medicine, Columbus, USA.

Electromyography and Clinical Neurophysiology
|December 1, 1996
PubMed
Summary
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Neuropsychological testing after concussion reveals abnormalities in middle latency auditory evoked potentials (MLR). These findings suggest potential subcortical or cortical disturbances following head trauma.

Area of Science:

  • Neuroscience
  • Neurology
  • Audiology

Background:

  • Minor head trauma, or concussion, can lead to controversial neuropsychiatric sequelae.
  • While clinical and imaging studies often show no alterations, neuropsychological and neuropathological abnormalities have been reported.
  • Neurophysiologic diagnostic tests may reveal changes in postconcussive syndrome.

Purpose of the Study:

  • To investigate neurophysiologic changes in individuals experiencing prolonged postconcussive symptoms.
  • To evaluate the utility of middle latency auditory evoked potentials (MLR) and slow vertex responses (SVR) in assessing postconcussive syndrome.

Main Methods:

  • Recorded MLR and SVR in 20 individuals with cognitive difficulties, behavioral changes, dizziness, and headache post-concussion.

Related Experiment Videos

  • MLR utilized alternating polarity clicks (70 dB SL, 4 Hz), with 50 ms analysis time and 20-1000 Hz filter.
  • SVR used rarefaction clicks (0.5 Hz), with 500 ms analysis time and 1-50 Hz filter.
  • Main Results:

    • Reduced amplitude of Na and Pa MLR components observed in postconcussion patients compared to controls.
    • Significantly longer Pa latency in patients.
    • SVR amplitudes were longer in concussed individuals, but latency and amplitude differences were not statistically significant.

    Conclusions:

    • Observed MLR changes may indicate posttraumatic disturbances in subcortical generators or modulating cortical structures.
    • Middle and long-latency auditory evoked potentials show potential as diagnostic tools for evaluating postconcussive neuropsychiatric symptoms.