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Is the automatic atrial defibrillator a promising approach?
J C Griffin1, G M Ayers, J Adams
1InControl Inc., Redmond, WA 98052, USA.
Journal of Cardiovascular Electrophysiology
|December 1, 1996
Summary
Atrial fibrillation, a common heart rhythm disorder, can be treated with low-energy electrical shocks. Implantable devices show promise for managing recurring episodes of this condition.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Atrial fibrillation is a prevalent arrhythmia with significant healthcare resource utilization.
- It causes loss of atrial contraction and impairs cardiac rate control.
- Previous animal studies showed feasibility of intravenous atrial defibrillation.
Purpose of the Study:
- To evaluate the effectiveness and safety of low-energy atrial defibrillation.
- To explore the potential of implantable devices for managing drug-refractory atrial fibrillation.
Main Methods:
- Intravenous electrode placement for atrial defibrillation.
- Delivery of low-energy electrical shocks synchronized to the R wave.
- Assessment of shock efficacy in converting atrial fibrillation.
- Evaluation of safety, particularly concerning preceding RR intervals.
Main Results:
- Low-energy shocks were effective in converting atrial fibrillation.
- Shocks were safe when delivered synchronously to the R wave and without short preceding RR intervals.
- Preliminary data suggests potential benefit from small implanted devices for recurrent, refractory cases.
Conclusions:
- Low-energy atrial defibrillation is effective and safe under specific conditions.
- Implantable devices represent a promising therapeutic option for patients with persistent, drug-refractory atrial fibrillation.