Probable nefazodone-induced mania in a patient with unreported bipolar disorder

H A Zaphiris¹, G D Blaisdell, D M Jermain

¹Department of Psychiatry and Behavioral Sciences, Texas A&M University College of Medicine, Scott & White Hospital and Clinic, Temple 76508, USA.

Annals of Clinical Psychiatry : Official Journal of the American Academy of Clinical Psychiatrists

|December 1, 1996

Abstract:

Nefazodone is a new antidepressant exhibiting properties of selective serotonin reuptake inhibition and serotonin-2 receptor antagonism. There has been only one other published case of induction of mania in a patient treated with nefazodone. This report describes a second case of probable induction of mania with nefazodone therapy and briefly reviews clinical and theoretical considerations involved in this process.

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Abstract:

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