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Meleda disease: report of two cases investigated by electron microscopy
E Frenk1, D Guggisberg, B Mevorah
1University Department of Dermatology, Lausanne, Switzerland.
Dermatology (Basel, Switzerland)
|January 1, 1996
Abstract:
We report 2 cases of clinically typical Meleda disease in a family from Herzegovina. Electron microscopy did not reveal major ultrastructural anomalies of keratinization; however, the transition from stratum granulosum to stratum corneum appeared to occur less abruptly than normally by a stepwise process suggesting a slowing down of terminal cornification.