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[Polycythemia vera progressing to acute lymphoblastic leukemia after 13 years]
[Rinsho Ketsueki] the Japanese Journal of Clinical Hematology
|December 1, 1996
Summary
Polycythemia vera (PV), a myeloproliferative neoplasm, can transform into acute lymphoblastic leukemia. This case highlights PV
Area of Science:
- Hematology
- Oncology
- Stem Cell Biology
Background:
- Polycythemia vera (PV) is a myeloproliferative neoplasm characterized by the overproduction of red blood cells.
- Transformation of PV into myeloid leukemia is well-documented, but lymphoid transformation is rare.
- Understanding the stem cell origin of PV is crucial for comprehending its potential to evolve into lymphoid malignancies.