[The binding of dyes of fibrinogen]

Examinations performed by means of the agargel-electrophoresis, immunoelectrophoresis, discelectrophoresis, and chromatography on gel in human plasma and preparations of fibrinogen revealed that fibrinogen will form complexes with 18 examined dyes of different chemical structure, from a total amounting to 46. The findings indicate a marked affinity of fibrinogen towards small molecules in general. In nearly all complex forming colour materials, fibrinogen could be identified by immunodiffusion in the colour-blood supernatant liquid. The physiological significance of the binding capacity of fibrinogen is discussed.