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Visualizing Genetic Variants, Short Targets, and Point Mutations in the Morphological Tissue Context with an RNA In Situ Hybridization Assay
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Phenotypic changes induced by wild type and variant c-src genes carrying C-terminal sequence alterations

B A Yatsula1, J Plachy, A Mikhailik

  • 1Unité Mixte de Recherche 146 du Centre National de la Recherche Scientifique, Institut Curie, Orsay, France.

Oncogene
|December 19, 1996
PubMed
Summary

The oncogenic properties of the c-src gene were investigated. Mutation of tyrosine 527 and C-terminal extension together fully activated c-src

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