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Microcystic meningioma. A case report
1Department of Pathology, College of Medicine, Hanyang University, Seoul, Korea.
Journal of Korean Medical Science
|December 1, 1996
Summary
Microcystic meningioma, a rare brain tumor variant, presents with unique cellular structures and fluid-filled spaces. This case report details a typical example found in the falx cerebri, confirming its distinct nature.
Area of Science:
- Neuropathology
- Oncology
Background:
- Meningiomas are tumors arising from the meninges, the membranes surrounding the brain and spinal cord.
- Microcystic meningioma is a recognized morphological subtype with specific histological features.
Observation:
- A case of microcystic meningioma occurred in the falx cerebri of a 41-year-old male patient.
- The tumor exhibited characteristic histological findings, including loose texture, microcysts, and stellate, vacuolated tumor cells with long cytoplasmic processes.
- Nests of meningothelial whorls were also present.
Findings:
- Immunohistochemical analysis revealed diffuse positivity for vimentin, epithelial membrane antigen (EMA), and S-100 protein.
- Ultrastructural examination confirmed the tumor's meningiomatous origin.
Implications:
- This case reinforces the distinct pathological identity of microcystic meningioma.
- Understanding its specific characteristics aids in accurate diagnosis and classification of meningiomas.