[The pathokinesis of vascular brain lesions]

Pathokinesis as the chain reaction included development and self-regulation of pathological processes which manifested themselves by different forms of cerebrovascular pathology was analysed basing on 5-year follow-up of 200 patients with initial forms of cerebrovascular deficiency and examination of patients with discirculatory encephalopathy (in 100 of them stroke had developed during this time) as well as the data on 873 patients with stroke. Pathokinetic significance of risk factors, conditions predisposing to stroke development and stroke direct reasons are characterised as well as therapy of different intensity. The possibilities of the correction of some pathokinetic mechanisms by means of emergent therapy as well as the role of some uncorrectable factors (biological and situational ones) were defined too. The pathokinetic peculiarities of the main forms of insult were defined more precisely in relation to on the degree of individual compensatory abilities.