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Updated: Aug 17, 2026

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
Published on: August 30, 2020
Diagnosis of spontaneous subarachnoid hemorrhage
1University of Iowa Hospitals and Clinics, Iowa City 52242, USA.
Abstract:
Spontaneous subarachnoid hemorrhage is usually the result of rupture of an intracranial saccular aneurysm or arteriovenous malformation. The hemorrhage is typically a cataclysmic event, heralded by severe headache, meningeal signs and neurologic dysfunction. About one-half of patients with aneurysmal rupture experience "sentinel headaches" days to weeks before a major hemorrhage. Diagnosis at this stage may permit treatment before the occurrence of a devastating neurologic event. Clinical suspicion of subarachnoid hemorrhage should be confirmed by computed tomographic evaluation. Initial treatment of patients with spontaneous subarachnoid hemorrhage includes resuscitation and/or stabilization, management of acute effects of the hemorrhage, and prompt referral for neurosurgical treatment.
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