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Updated: Aug 10, 2026

A Rat Carotid Balloon Injury Model to Test Anti-vascular Remodeling Therapeutics
Published on: September 19, 2016
History of carotid surgery
1Department of Neurological Surgery, University of Oklahoma College of Medicine, Oklahoma City, Oklahoma 73106, USA.
Abstract:
The history of carotid surgery begins not with the detailing of the various surgical procedures, as might be imagined, but with a history of the understanding of the nature of carotid occlusive disease. It was only through an understanding of the basis of this disease that a rational surgical treatment could be formulated. Following a well-characterized disease process, surgical strategies were developed and refined during the first half of the twentieth century. After these surgical techniques had been refined, a number of national and international trials were performed to better determine which patients were candidates for surgical intervention. Currently, endovascular treatment stands on the horizon as a new therapeutic modality with which carotid occlusive disease may be treated.

