Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gene therapy strategies for leukemia

S E Braun1, K Chen, M Battiwalla

  • 1Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202-5121, USA.

Molecular Medicine Today
|January 1, 1997
PubMed
Summary

Gene therapy offers novel strategies for leukemia treatment, targeting molecular mechanisms and immune responses. Research focuses on improving gene delivery to enhance patient survival in leukemia.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A remarkable rate acceleration of the Baylis-Hillman reaction.

Chemical communications (Cambridge, England)·2002
Same author

[The thumb reconstruction by transferring the injured index finger with pedicles].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery·2002
Same author

[A new practical route to stereospecific synthesis of (S)-(-)-ofloxacin].

Yao xue xue bao = Acta pharmaceutica Sinica·2002
Same author

Effects of image resolution on autoradiographic measurements of posterior cingulate activity in PDAPP mice: implications for functional brain imaging studies of transgenic mouse models of Alzheimer's Disease.

NeuroImage·2002
Same author

Heart rate dynamics in monoamine oxidase-A- and -B-deficient mice.

American journal of physiology. Heart and circulatory physiology·2002
Same author

[Clinical study on treatment of nasopharyngeal carcinoma by radio- and chemotherapy with supplementary moxibustion on Shenque point].

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine·2002

Area of Science:

  • Oncology
  • Molecular Biology
  • Immunology

Background:

  • Leukemia poses a significant challenge, necessitating novel therapeutic approaches.
  • Current treatments have limitations, driving the exploration of innovative strategies.
  • Gene therapy presents a promising avenue for combating leukemia.

Purpose of the Study:

  • To review diverse gene therapy strategies for leukemia treatment.
  • To highlight molecular and immunological approaches to cancer therapy.
  • To discuss advancements in gene delivery for improved patient outcomes.

Main Methods:

  • Review of scientific literature on gene therapy for leukemia.
  • Analysis of various gene therapy modalities, including antisense oligonucleotides, ribozymes, and gene transfer.
  • Examination of gene marking and suicide gene strategies.

Main Results:

  • Gene therapy targets leukemia's molecular mechanisms and can elicit anti-tumor immunity.
  • Gene marking aids in understanding leukemia relapse post-transplantation.
  • Suicide genes can modulate graft-versus-host disease.

Conclusions:

  • Gene therapy offers diverse strategies to improve leukemia patient survival.
  • Overcoming gene delivery challenges is crucial for therapeutic success.
  • Continued research in gene therapy holds significant promise for leukemia treatment.

Related Experiment Videos