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Parasystole associated with fixed coupling ventricular ectopic activity

S Gavrilescu, C Luca

    Cor Et Vasa
    |January 1, 1977
    PubMed
    Summary
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    Ventricular parasystole and fixed coupling ectopic beats are closely related mechanisms in cardiac arrhythmias. Mathematical relationships and His bundle electrography help explain their occurrence and ventricular origin.

    Area of Science:

    • Cardiology
    • Electrophysiology

    Background:

    • Ventricular parasystole is a rare arrhythmia characterized by ectopic beats originating in the ventricles.
    • Fixed coupling describes a consistent R-R interval between a preceding QRS complex and a subsequent ectopic beat.

    Observation:

    • The study observed ventricular parasystole and fixed coupling ectopic beats in five patients.
    • Intermittent ventricular parasystole and bigeminism were noted in two cases.
    • One patient exhibited a spontaneous transition from ventricular parasystole to parasystolic tachycardia with reverse coupling, and then to ventricular bigeminy.

    Findings:

    • Ventricular parasystole and fixed coupling extrasystolic activity appear to be closely related mechanisms.
    • In two cases, a mathematical relationship between sinus and parasystolic discharge rates explained periodic fixed coupling.

    Related Experiment Videos

  • His bundle electrography confirmed the ventricular origin of ectopic beats in one patient.

    • Implications:

    • Understanding the relationship between ventricular parasystole and fixed coupling is crucial for diagnosing and managing complex ventricular arrhythmias.
    • These findings highlight the utility of electrophysiological studies in elucidating the mechanisms of ectopic beats.
    • Further research may refine therapeutic strategies for patients with these arrhythmias.