Related Experiment Videos
[Acquired autoantibodies against human factor VIII: a new case]
N Cailleux1, H Levesque, H Courtois
1Département de Médecine Interne, Hôpital de Boisguillaume, CHU de Rouen.
Journal Des Maladies Vasculaires
|January 1, 1996
Summary
A prolonged partial thromboplastin time indicates a defect in the intrinsic coagulation pathway. This case highlights the diagnostic approach for postpartum hemorrhage due to factor VIII inhibitors.
Area of Science:
- Hematology
- Coagulation Disorders
Background:
- Prolonged partial thromboplastin time (aPTT) with normal prothrombin time (PT) suggests an intrinsic pathway coagulation defect.
- Hemorrhage necessitates a rapid diagnostic approach to identify the specific coagulation factor deficiency or inhibitor.