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Updated: Aug 11, 2026

In Situ Ca2+ Imaging of the Enteric Nervous System
Published on: January 29, 2015
Vasoactive intestinal polypeptide containing neurones in monkey medial prefrontal cortex (mPFC): colocalisation with
1University Department of Pharmacology, Oxford, UK. paul.gabbott@pharm.ox.ac.uk
Abstract:
Neurones immunoreactive for vasoactive intestinal polypeptide (VIP) were studied in monkey medial prefrontal cortex. The majority (78.0%) of VIP+ neurones were bipolar cells located mainly in layers 2/3. Calretinin (CR) immunoreactivity was colocalised in 80.5% of VIP+ neurones. Furthermore, VIP+ puncta formed pericellular baskets around GABA immunonegative somata in layers 2/3. These results indicate that VIP/CR are colocalised in some bipolar cells and superficial pyramidal somata are likely targets of VIP+ neurones.
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