Obstetric complications and rheumatic disease

This article summarizes common fetal and maternal complications of pregnancy and emphasizes special problems in women who have systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, dermatomyositis, polymyositis, and Sjögren's syndrome. Joint management of pregnancies in these women requires an understanding of the obstetric management of the complications. Pathophysiology and treatment options for preterm-labor, preterm premature rupture of membranes, abnormal fetal growth, and hypertensive disorders of pregnancy are reviewed.