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Cell-specific mechanisms of estrogen receptor in the pituitary gland
F Demay1, S Geffroy, C Tiffoche
1Laboratoire d'Endocrinologie Moléculaire de la Reproduction, Centre National de la Recherche Scientifique, Rennes, France.
Cell Biology and Toxicology
|December 1, 1996
Abstract:
Analysis of the mechanism of action of estrogen receptor shows protein and mRNA polymorphism within distinct pituitary receptor-positive cells. The lactotropes exhibit unique properties in these mechanisms that distinguish them from gonadotropes. Therefore, this cell type constitutes an especially interesting model in the male as well as in the female for estrogen receptor studies.