Research in orthokeratology. Part VI: statistical and clinical analyses

In this paper, the rationale, statistical methods and results of this study are given. Specifically, it is shown that contact lenses produce clinical effects on the eye which are statistically significant. Moreover, the orthokeratology procedure was found to produce more corneal and refractive change than conventional contact lens wear. Variability and predictability of data are discussed along with pertinent clinical considerations. Certain factors and their influence on corneal change are examined and quantified.