Related Experiment Videos
Prospective randomized study of sulindac versus calcium and calciferol for upper gastrointestinal polyps in familial
F Seow-Choen1, V Vijayan, V Keng
1Department of Colorectal Surgery, Singapore General Hospital, Singapore.
The British Journal of Surgery
|December 1, 1996
Abstract:
Eighteen patients with familial adenomatous polyposis (FAP) who had previously undergone colectomy but had upper gastrointestinal polyps were studied in a double-blind randomized crossover trial comparing sulindac with calcium and calciferol. Sulindac produced a reduction in the crypt proliferation index in the gastric epithelium of patients but did not significantly affect duodenal mucosa. Calcium with calciferol did not have any effects on crypt proliferation index in patients with FAP.