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Lupus erythematosus profundus associated with neonatal lupus erythematosus
1Department of Dermatology, Aichi Medical University, Japan.
The British Journal of Dermatology
|January 1, 1997
Insights
Neonatal lupus erythematosus can present with both skin lesions and deeper tissue involvement. This case highlights persistent facial lupus erythematosus profundus in an infant, indicating potential long-term effects.
Area of Science:
- Dermatology
- Pediatrics
- Immunology
Background:
- Neonatal lupus erythematosus (NLE) is a rare autoimmune condition affecting infants.
- It is typically associated with maternal autoantibodies, primarily anti-Ro/SSA and anti-La/SSB.
Observation:
- This report details a female infant diagnosed with NLE.
- The infant presented with subtle discoid lesions and simultaneous lupus erythematosus profundus (LEP) affecting the face.
Findings:
- The facial LEP lesions in this infant showed persistent depression.
- These findings were noted to be evident even at 4 years of age.
Implications:
- This case underscores the potential for significant and lasting facial disfigurement from LEP in NLE.
- It suggests the need for long-term monitoring and management strategies for NLE patients with profundus involvement.
Abstract:
A female infant with neonatal lupus erythematosus had scanty discoid lesions and concurrent lupus erythematosus profundus on the face. Depression of lupus erythematosus profundus lesions was still evident at 4 years of age.