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Interventional atrioseptostomy by application of monopolar high-frequency alternating current. In vitro evaluation of
R G Grabitz1, S Handt, H J Vanopbroeke
1Department of Pediatric Cardiology, Aachen University of Technology, Germany.
Rationale And Objectives:
The authors evaluate the use of a new device for interventional creation of atrial septal defects (ASD) working with high-frequency alternating current in an in vitro study with porcine atria.
Methods:
The device consists of a symmetrical cage of six superelastic monofile wires, including a microthermistor that is placed via a catheter into a punctured hole in the porcine foramen ovale. The device is used as a differential electrode for monopolar, temperature-controlled application of high-frequency alternating current for thermal modelling of ASD.
Results:
Application of current for 60 seconds caused temperature-dependent, sized ASDs.
Conclusion:
In vivo animal studies to evaluate possible side effects and long term patency of the ASDs are justified and warranted.