Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Origin, maturation and antigen presenting function of dendritic cells

M Cella1, F Sallusto, A Lanzavecchia

  • 1Basel Institute for Immunology, Grenzacherstrasse 487, CH4005 Basel, Switzerland.

Current Opinion in Immunology
|February 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A scoping review of targeted psychological interventions for negative symptoms in schizophrenia.

Schizophrenia research·2026
Same author

Tumor-targeted IL2 promotes specific CD8<sup>+</sup> T cells private clonal expansion enhancing lymphoma control.

Journal of experimental & clinical cancer research : CR·2026
Same author

Chronic mild maternal stress modulates the immune response at the maternal-fetal interface and affects the growth and mortality of the offspring.

Placenta·2025
Same author

Lipopolysaccharide-induced subclinical infection affects pregnancy and impairs offspring development in an early gestation rat model.

Placenta·2025
Same author

Translational assessment of anhedonia components: Significant associations between reward anticipation measured via behavioural task performance, daily smartphone reports, and general anhedonia questionnaires.

Behaviour research and therapy·2024
Same author

Autoreactive T cells target peripheral nerves in Guillain-Barré syndrome.

Nature·2024

Dendritic cells are crucial for initiating immune responses by capturing antigens and stimulating T cells. Future research aims to harness these cells as natural adjuvants for therapeutic applications.

Area of Science:

  • Immunology
  • Cell Biology

Background:

  • Dendritic cells (DCs) are key immune cells responsible for antigen capture, migration, and T cell activation.
  • Recent advancements have elucidated DC origins, heterogeneity, antigen uptake mechanisms, and migration/maturation signals.

Purpose of the Study:

  • To summarize recent progress in understanding dendritic cell biology.
  • To highlight the potential of dendritic cells as therapeutic adjuvants.

Main Methods:

  • Review of recent scientific literature on dendritic cells.
  • Analysis of immunological mechanisms involving dendritic cells.

Main Results:

  • Dendritic cells are specialized antigen-presenting cells crucial for initiating adaptive immunity.

Related Experiment Videos

  • Understanding DC function is advancing rapidly, covering their origin, diversity, and activation pathways.

    • Conclusions:

    • Dendritic cells are natural adjuvants that potentiate T cell responses.
    • Therapeutic strategies utilizing dendritic cells are anticipated in the near future.