Imaging of primary multifocal osseous lymphoma
J W Melamed1, S Martinez, C J Hoffman
1Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA.
Skeletal Radiology
|January 1, 1997
Summary
Primary multifocal osseous lymphoma (PMOL) distribution is best seen with bone scans, but MRI shows marrow involvement. Plain radiographs are best for assessing treatment response in PMOL.
Area of Science:
- Oncology
- Radiology
- Hematology
Background:
- Primary multifocal osseous lymphoma (PMOL) is a rare bone malignancy.
- Understanding its imaging characteristics is crucial for diagnosis and treatment monitoring.
Purpose of the Study:
- To review experience with PMOL.
- Characterize pre- and post-treatment imaging features.
- Correlate imaging findings with clinical outcomes.
Main Methods:
- Retrospective review of 8 patients with PMOL.
- Analysis of bone radiographs, bone scans, CT, and MRI.
- Evaluation of lesion number, distribution, appearance, and treatment response.
Main Results:
- Bone scans identified 63 lesions, MRI 36, and radiographs 16.
- Lesions commonly occurred around the knee, skull, distal femur, and proximal tibia.
- Plain radiographs showed healing/progression correlating with clinical outcome.
Conclusions:
- Bone scans best assess PMOL distribution.
- MRI reveals greater marrow involvement and detects pelvic lesions.
- Radiographs are best for assessing treatment response, despite underestimating disease extent.
